Currently the sole confirmed reason for mesothelioma cancer is contact with asbestos. Medical diagnosis of mesothelioma is usually difficult, due to the fact mesothelioma symptoms might not appear till 3-5 decades following contact with asbestos fiber and signs and symptoms resemble those of numerous other conditions. The significance of early diagnosis of mesothelioma cancer can't be overemphasized. Below you will learn about conventional and new methods of mesothelioma cancer diagnosis.


FDA (the Food and Drug Administration) in January 2007 authorised the MESOMARK test to assist monitor response to treatment method in malignant mesothelioma patients. The MESOMARK test represents the start of a brand new era in tracking mesothelioma cancer malignancies. As the first in-vitro analyze for people with this dangerous disease, it will eventually allow doctors to better identify recurrence and monitor treatments for patients.

The MESOMARK test package was created to determine levels of a biomarke, mesothelin in serum. Biomarkers are ingredients present in greater than normal concentrations within the blood, urine or body tissues of individuals with certain kinds of cancer. The analyze could be used to observe patients proved as having mesothelioma cancer, for recurrence in patients following surgical treatment, and for measuring reaction to therapies.

Existing diagnostic tests are not perfect for quantification of changes in tumor volume, that is key to handling the illness. Since the MESOMARK results correlate with tumor volume, it gives a much required instrument for checking patient condition.

Using a simple blood test MESOMARK are making it possible to observe reaction to treatment and also to identify recurrence subsequent treatment. This gives a significant head start to people racing against this desease.

People wanting to participate in MESOMARK testing will have to supply one or two samples of blood. The blood samples will then be delivered to a nationwide reference research lab for testing. Along with other clinical and laboratory information received from your medical doctor, conclusions about your treatment method and care might be made easier. You could stop testing whenever you want.

LDCT Evaluated for Early Detection of Lung Cancer and Mesothelioma

Based on the latest and promising research in The Oncologist, scientists discovered that LDCT (Low Dose Computed Tomography) could be useful in discovering pleural issues such as the early diagnosis of malignant pleural cancer and mesothelioma cancer. Scientists evaluated LDCT, i.e., spiral or helical computed tomography, screening of people subjected to asbestos. LDCT demonstrated more efficient at early recognition of lung cancer compared to a chest radiograph (x–ray).

Read more about the results of LDCT study

Traditional methods of diagnosis mesothelioma

Diagnosis mesothelioma cancer starts with overview of the patient's medical history, including any history of exposure to asbestos. A physical test is carried out, followed by chest X-ray and quite often lung function tests. The X-ray may show pleural thickening typically observed after exposure to asbestos and increases suspicion of mesothelioma cancer. A CT (or CAT) scan or an MRI can also be helpful. A CT scan is a number of detailed pictures of places within the body produced by a computer associated with an x-ray machine. In an MRI, a powerful magnet linked with a pc is utilized to produce detailed photos of areas inside the body. These photos are observed on a monitor and may also be printed. If a large quantity of fluid occurs, abnormal cells could be recognized by cytology if this fluid is aspirated with a squirt. For pleural liquid this is achieved with a pleural tap or chest drain, in ascites with an paracentesis or ascitic drain and in a pericardial effusion with pericardiocentesis. While lack of malignant cells on cytology doesn't totally exclude mesothelioma, it can make it a lot more unlikely, particularly if an alternate examination can be done (e.g. tuberculosis, heart failure).

If cytology is positive or a plaque is regarded as suspicious, a biopsy is needed to confirm a diagnosis of mesothelioma.  In a biopsy, a surgeon or a medical oncologist (a doctor who specializes in diagnosing and treating cancer) removes a sample of tissue for examination under a microscope by a pathologist. A biopsy may be done in different ways, depending on where the abnormal area is located.
If the cancer is in the chest, the doctor may perform a thoracoscopy. In this procedure, the doctor makes a small cut through the chest wall and puts a thin, lighted tube called a thoracoscope into the chest between two ribs. Thoracoscopy allows the doctor to look inside the chest and obtain tissue samples. If the cancer is in the abdomen, the doctor may perform a peritoneoscopy. To obtain tissue for examination, the doctor makes a small opening in the abdomen and inserts a special instrument called a peritoneoscope into the abdominal cavity. If these procedures do not yield enough tissue, more extensive diagnostic surgery may be necessary.

If the diagnosis is mesothelioma, the doctor will want to learn the stage (or extent) of the disease. Staging involves more tests in a careful attempt to find out whether the cancer has spread and, if so, to which parts of the body. Knowing the stage of the disease helps the doctor plan treatment.
Mesothelioma is described as localized if the cancer is found only on the membrane surface where it originated. It is classified as advanced if it has spread beyond the original membrane surface to other parts of the body, such as the lymph nodes, lungs, chest wall, or abdominal organs.

about misdiagnosis mesothelioma